Shinsuke Matsuzaki Selected Research

Dysbindin

6/2015	Molecular basis of major psychiatric diseases such as schizophrenia and depression.
10/2014	Behavioral characterization of mice overexpressing human dysbindin-1.
1/2011	Reduced rate of neural differentiation in the dentate gyrus of adult dysbindin null (sandy) mouse.
1/2010	Dysbindin regulates the transcriptional level of myristoylated alanine-rich protein kinase C substrate via the interaction with NF-YB in mice brain.
2/2009	Dysbindin engages in c-Jun N-terminal kinase activity and cytoskeletal organization.
8/2008	Behavioral abnormalities and dopamine reductions in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia.
6/2007	High dopamine turnover in the brains of Sandy mice.
6/2006	Hyperactivation of midbrain dopaminergic system in schizophrenia could be attributed to the down-regulation of dysbindin.

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Shinsuke Matsuzaki Research Topics

Disease

15	Schizophrenia (Dementia Praecox) 06/2015 - 06/2006
7	Alzheimer Disease (Alzheimer's Disease) 07/2022 - 08/2002
5	Hyperalgesia 12/2021 - 01/2017
4	Neuralgia (Stump Neuralgia) 01/2019 - 01/2017
4	Mental Disorders (Mental Disorder) 06/2015 - 07/2007
3	Bipolar Disorder (Manic Depressive Psychosis) 01/2011 - 04/2008
2	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2022 - 10/2007
2	Pain (Aches) 12/2021 - 11/2017
2	Cicatrix (Scar) 10/2019 - 01/2017
2	Wounds and Injuries (Trauma) 10/2019 - 01/2015
2	Neuroinflammatory Diseases 01/2019 - 11/2017
2	Hypoxia (Hypoxemia) 02/2005 - 03/2004
1	Tauopathies 07/2022
1	Hypersensitivity (Allergy) 12/2021
1	Contact Dermatitis (Eczema, Contact) 01/2020
1	Neoplasms (Cancer) 01/2020
1	Limited Scleroderma 10/2019
1	Type 2 Diabetes Mellitus (MODY) 01/2019
1	Intractable Pain 03/2018
1	Peripheral Nerve Injuries 03/2018
1	Hypertrophic Cicatrix (Hypertrophic Scar) 01/2017
1	Keloid 01/2017
1	Autistic Disorder (Autism) 01/2014
1	Alopecia Areata 03/2013
1	Dwarfism 10/2009
1	Fasciculation (Fasciculations) 07/2007
1	Neuroblastoma 05/2004

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 10/2019 - 02/2005
8	DysbindinIBA 06/2015 - 06/2006
4	Messenger RNA (mRNA)IBA 10/2019 - 04/2008
4	Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)IBA 06/2015 - 07/2007
3	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2019 - 11/2017
3	pericentrinIBA 10/2009 - 04/2008
2	tau Proteins (tau Protein)IBA 07/2022 - 05/2004
2	clozapine N-oxideIBA 12/2021 - 01/2020
2	LigandsIBA 01/2020 - 11/2017
2	Interleukin-13IBA 10/2019 - 01/2017
2	CytokinesIBA 10/2019 - 11/2017
2	TC 2559IBA 01/2019 - 03/2018
2	Presenilin-1IBA 01/2010 - 03/2008
2	Amyloid beta-PeptidesIBA 01/2010 - 03/2008
2	Presenilin-2IBA 10/2007 - 08/2002
1	UbiquitinIBA 07/2022
1	pexidartinibIBA 12/2021
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2020
1	diphenylcyclopropenoneIBA 01/2020
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2020
1	Interleukin-4 (Interleukin 4)IBA 10/2019
1	Extracellular Matrix ProteinsIBA 10/2019
1	PeriostinIBA 10/2019
1	AminesIBA 01/2019
1	LipopolysaccharidesIBA 01/2019
1	SaporinsIBA 01/2019
1	sazetidine-AIBA 03/2018
1	Amyloid (Amyloid Fibrils)IBA 01/2018
1	ChemokinesIBA 11/2017
1	rho-Associated KinasesIBA 01/2017
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 01/2017
1	Endothelin-1 (Endothelin 1)IBA 01/2017
1	CollagenIBA 01/2015
1	Matrix Metalloproteinases (MMPs)IBA 01/2015
1	GlycosaminoglycansIBA 01/2015
1	Metalloproteases (Metalloproteinases)IBA 01/2015
1	Neurotransmitter Agents (Neurotransmitter)IBA 10/2014
1	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 01/2014
1	N-Ethylmaleimide-Sensitive Proteins (N-Ethylmaleimide-Sensitive Fusion Protein)IBA 01/2014
1	Carrier Proteins (Binding Protein)IBA 01/2014
1	Pharmaceutical PreparationsIBA 10/2010
1	Yi-Gan SanIBA 10/2010
1	DNA (Deoxyribonucleic Acid)IBA 10/2009
1	Peptides (Polypeptides)IBA 09/2008
1	Adenylyl Cyclases (Adenylyl Cyclase)IBA 09/2008
1	Dopamine (Intropin)FDA LinkGeneric 08/2008
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 04/2008
1	RNA Precursors (Precursor, mRNA)IBA 10/2007
1	RNA (Ribonucleic Acid)IBA 10/2007
1	Protein Isoforms (Isoforms)IBA 10/2007
1	Pituitary Adenylate Cyclase-Activating Polypeptide ReceptorsIBA 07/2007
1	kendrinIBA 07/2007
1	Tyrosine (L-Tyrosine)FDA Link 02/2005
1	Transcription Factors (Transcription Factor)IBA 02/2005
1	Serine (L-Serine)FDA Link 02/2005
1	Threonine (L-Threonine)FDA Link 02/2005
1	AluminumIBA 03/2004

Therapy/Procedure

3	Ligation 01/2020 - 01/2017
3	Drug Therapy (Chemotherapy) 01/2019 - 11/2017
1	Therapeutics 11/2017
1	Transjugular Intrahepatic Portasystemic Shunt 02/2015
1	Electroacupuncture 03/2013